Focus on multiple myeloma treatment: Witnessing a transformation

David Cooney | 15th March 2016

I get very excited by science, specifically pharmacology, and when I was studying drug development I used to read case studies about the impact ground-breaking drugs had, and imagine what it must have been like to be part of that success. I used to harass an old mentor of mine who was involved in the Herceptin launch for stories about introducing such an innovative treatment, hoping one day I’d get a chance to be part of such a transformation in care.

I’m now part of a team at Blue Latitude Health working in multiple myeloma (MM), and with each publication that emerges, it’s clear that we are witnessing a transformation in the treatment of multiple myeloma. In this article, I will take you through how that transformation has happened, and where the treatment of multiple myeloma is heading.

The Therapeutic Index of multiple myeloma therapies

“It is easy to be overwhelmed by hype in cancer research, with promising new discoveries often portrayed as so-called game changers….but myeloma is a rare exception” [sic]

was the opening of a recent editorial in the Lancet on multiple myeloma. To appreciate the context of this statement we need to consider what treatment options were like for myeloma patients in the past.   

If we reflect on what the treatment options were 10 years ago, two drugs stand out – melphalan and thalidomide. Melphalan, a distant cousin of the mustard gas used to kill World War I soldiers, and thalidomide, the infamous chiral drug which caused birth defects in the 1960s. These drugs have been shown to be efficacious options for patients with MM, but with a low therapeutic index. This meant significant cost in terms of toxicity, and marginal impact on the overall survival of patients.

 

Download the full article to read more about the future of multiple myeloma treatment.

Meet the CEO behind ReNeuron’s cutting-edge stem cell therapies

Natasha Cowan | 18th April 2018

Blue Latitude Health speaks to Olav Hellebo, CEO of ReNeuron, to find out about the biotech’s latest innovation in stem cell therapy and to learn his perspective on navigating the challenges that come with developing products in this complex market.

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Customer journeys: a tool for behaviour change

Natasha Cowan, Elisa del Galdo | 13th April 2018

In this Q&A, BLH speaks to Director and Head of Customer Experience Elisa del Galdo to learn how she uses customer journeys to drive innovation and facilitate behaviour change.

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Perspective on the power of insight

Blue Latitude Health | 4th April 2018

Good insight gives you the tools to create innovative products and services that meet customer’s needs at the point of need. In this issue of Perspective magazine, our in-house insight experts unite to reveal the best practical tools, tips and knowledge for harnessing insight to empower your customers and inspire innovation.

 

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